IGKV5-2

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGKV5-2 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,491 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGKV5-2-associated proteins across cancer lineages are MZB1, IL16, and RASAL3. Each is linked with IGKV5-2 in more than 9 cancer types. Because this analysis shows association rather than direction, both IGKV5-2-to-partner and partner-to-IGKV5-2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV5-2→partner) and Y-score (partner→IGKV5-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVMZB1 →+1.372+1.675<.001<.001310
BRCAIL16 →+0.609+1.927<.001<.001310
BRCARASAL3 →+0.409+1.619<.001<.00139
BRCACD38 →+1.114+1.922<.001<.00139
BRCACD48 →+0.880+1.711<.001<.00138
BRCADOCK2 →+0.555+1.931<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,491 associations by consensus.

Exploration