Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, IGKV5-2 mutation is significantly associated with the RNA expression of many other genes, with 171 significant associations in total. UCEC shows the largest number of these associations.
The most reproducible IGKV5-2-associated genes across cancer lineages are RDXP2, RCC2P1, and MTCO3P9. Each is linked with IGKV5-2 in more than 2 cancer types. Because this analysis shows association rather than direction, both IGKV5-2-to-partner and partner-to-IGKV5-2 results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (IGKV5-2→partner) and Y-score (partner→IGKV5-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.