Across TCGA patient cohorts, IGKV3D-7 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,827 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible IGKV3D-7-associated GO terms across cancer lineages are B cell mediated immunity, Antibacterial humoral response, and Antimicrobial humoral response. Each is linked with IGKV3D-7 in more than 26 cancer types. Because this analysis shows association rather than direction, both IGKV3D-7-to-partner and partner-to-IGKV3D-7 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV3D-7→partner) and Y-score (partner→IGKV3D-7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	B cell mediated immunity →	+0.108	+0.977	<.001	<.001	3	27
THCA	Antibacterial humoral response →	+0.136	+0.907	<.001	<.001	3	27
THCA	Antimicrobial humoral response →	+0.088	+0.883	<.001	<.001	3	26
STAD	Immunoglobulin production →	+0.101	+1.621	<.001	<.001	3	26
ESCA	CD4-positive, alpha-beta T cell activation →	+0.066	+0.949	<.001	<.001	3	25
ESCA	CD4-positive, alpha-beta T cell differentiation →	+0.066	+0.962	<.001	<.001	3	25

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,827 associations by consensus.

Exploration

IGKV3D-7 survival (RNA) · tumor vs normal (RNA) · all IGKV3D-7 data types