IGKV2D-24

Across TCGA pan-cancer cohorts, IGKV2D-24 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated IGKV2D-24 data layer compared with 23 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in thymoma (THYM), where higher IGKV2D-24 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated IGKV2D-24 expression acts as an unfavorable survival marker.

THYM and LUAD are the cancer types where IGKV2D-24 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Median	III,IV	0.103	0.944	<.001	42	view →
LUAD	OS	Median	II,III,IV	0.090	0.709	<.001	12	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

IGKV2D-24–THYM (OS)

Open the THYM breakdown →