Across TCGA patient cohorts, IGKV1D-42 RNA expression is significantly associated with the RNA expression of many other genes, with 7,917 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible IGKV1D-42-associated genes across cancer lineages are IGHJ2, IGKV1-33, and IGHV3OR16-9. Each is linked with IGKV1D-42 in more than 32 cancer types. Because this analysis shows association rather than direction, both IGKV1D-42-to-partner and partner-to-IGKV1D-42 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV1D-42→partner) and Y-score (partner→IGKV1D-42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	IGHJ2 →	+3.590	+1.877	<.001	<.001	3	33
LUSC	IGKV1-33 →	+2.575	+2.114	<.001	<.001	3	33
LUSC	IGHV3OR16-9 →	+2.244	+2.156	<.001	<.001	3	33
LUAD	IGHV3-41 →	+1.878	+1.993	<.001	<.001	3	33
LUSC	IGKV1D-12 →	+2.300	+2.030	<.001	<.001	3	33
LUSC	IGHV1OR15-9 →	+2.654	+2.095	<.001	<.001	3	33

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,917 associations by consensus.

Exploration

IGKV1D-42 survival (RNA) · tumor vs normal (RNA) · all IGKV1D-42 data types