Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, IGKV1D-42 mutation is significantly associated with the RNA expression of many other genes, with 2,553 significant associations in total. UCEC shows the largest number of these associations.
The most reproducible IGKV1D-42-associated genes across cancer lineages are MIR7845, CPSF2, and ODF3B. Each is linked with IGKV1D-42 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGKV1D-42-to-partner and partner-to-IGKV1D-42 results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (IGKV1D-42→partner) and Y-score (partner→IGKV1D-42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.