Across TCGA patient cohorts, IGKJ4 protein abundance is significantly associated with the RNA expression of many other genes, with 11,852 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGKJ4-associated genes across cancer lineages are FCRL5, IRF4, and IGHV1OR15-9. Each is linked with IGKJ4 in more than 6 cancer types. Because this analysis shows association rather than direction, both IGKJ4-to-partner and partner-to-IGKJ4 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKJ4→partner) and Y-score (partner→IGKJ4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FCRL5 →	+1.154	+1.030	<.001	<.001	3	7
LSCC	IRF4 →	+1.355	+0.991	<.001	<.001	3	6
LSCC	IGHV1OR15-9 →	+1.263	+0.713	<.001	<.001	3	6
PDAC	IGHG4 →	+1.980	+0.722	.001	.001	3	5
BRCA	LILRB5 →	+0.697	+0.875	<.001	<.001	3	5
UCEC	AMPD1 →	+0.665	+0.965	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,852 associations by consensus.

Exploration

IGKJ4 survival (RNA) · tumor vs normal (RNA) · all IGKJ4 data types