IGIP

Across TCGA patient cohorts, IGIP RNA expression is significantly associated with the protein abundance of many other proteins, with 22,444 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible IGIP-associated proteins across cancer lineages are SEPTIN8, EFEMP2, and FBLN1. Each is linked with IGIP in more than 7 cancer types. Because this analysis shows association rather than direction, both IGIP-to-partner and partner-to-IGIP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGIP versus SEPTIN8 in OV, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGIP→partner) and Y-score (partner→IGIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SEPTIN8 →	+0.391	+0.694	.002	.001	3	8
PDAC	EFEMP2 →	+0.928	+0.473	<.001	<.001	3	7
OV	FBLN1 →	+1.079	+0.784	<.001	.001	3	7
OV	FERMT2 →	+0.615	+0.867	<.001	<.001	3	7
PDAC	TTI1 →	-0.355	-0.473	<.001	<.001	3	7
LSCC	DDX21 →	-0.576	-0.362	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,444 associations by consensus.

IGIP vs SEPTIN8 — OV

Explore this scatter interactively →