IGIP

Across TCGA cell cohorts, IGIP mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible IGIP-associated genes across cancer lineages are KLHL40 and GAGE12H. Each is linked with IGIP in more than 1 cancer types. Because this analysis shows association rather than direction, both IGIP-to-partner and partner-to-IGIP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KLHL40 grouped by IGIP-low versus IGIP-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGIP→partner) and Y-score (partner→IGIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	KLHL40 →	+0.006	+5.209	.006	.005	3	1
BLOOD_Lymphoma	GAGE12H →	+1.799	+5.209	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

KLHL40 by IGIP expression — BLOOD_Lymphoma

Explore this box plot interactively →