IGHVII-67-1

Across TCGA pan-cancer cohorts, IGHVII-67-1 RNA is linked to patient survival in 5 of 34 cancer types, making it the most broadly survival-associated IGHVII-67-1 data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher IGHVII-67-1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated IGHVII-67-1 expression acts as an unfavorable survival marker.

CESC, DLBC, and STAD are the cancer types where IGHVII-67-1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Tertile	All	0.182	0.742	<.001	72	view →
DLBC	DFS	Tertile	II,III,IV	0.065	0.829	<.001	54	view →
STAD	DFS	Tertile	All	0.221	0.568	.001	54	view →
COAD	OS	Tertile	II,III,IV	0.140	0.850	<.001	36	view →
SARC	OS	Tertile	All	0.022	0.861	<.001	36	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

IGHVII-67-1–CESC (DFS)

Open the CESC breakdown →