IGHVII-44-2

Across TCGA pan-cancer cohorts, IGHVII-44-2 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated IGHVII-44-2 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher IGHVII-44-2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated IGHVII-44-2 expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

KIRP, KICH, and UCEC are the cancer types where IGHVII-44-2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Tertile	All	0.132	0.695	<.001	126	view →
KICH	DFS	Tertile	All	0.081	0.904	<.001	90	view →
UCEC	DFS	Tertile	III,IV	0.538	0.810	.005	84	view →
LIHC	DFS	Tertile	All	0.404	0.585	.001	75	view →
STAD	OS	Tertile	II,III,IV	0.354	0.590	.002	63	view →
UCS	DFS	Tertile	IV	0.132	0.718	.002	36	view →
LGG	OS	Tertile	All	0.425	0.813	<.001	36	view →
LUAD	OS	Tertile	III,IV	0.528	0.679	.005	30	view →
HNSC	OS	Tertile	II,III,IV	0.372	0.723	.025	24	view →
ESCA	DFS	Tertile	All	0.142	0.512	<.001	18	view →
SKCM	OS	Tertile	All	0.432	0.298	.020	4	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

IGHVII-44-2–KIRP (OS)

Open the KIRP breakdown →