IGHVII-30-1

Across TCGA pan-cancer cohorts, IGHVII-30-1 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated IGHVII-30-1 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher IGHVII-30-1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated IGHVII-30-1 expression acts as an unfavorable survival marker, although some lineages such as ESCA and LIHC show a favorable association.

UCEC, SARC, and LUAD are the cancer types where IGHVII-30-1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	III,IV	0.053	0.588	.005	36	view →
SARC	DFS	Tertile	All	0.095	0.632	.002	30	view →
LUAD	DFS	Tertile	III,IV	0.206	0.670	.015	18	view →
ESCA	DFS	Tertile	All	0.779	0.507	.032	15	view →
TGCT	DFS	Tertile	All	0.123	0.685	.005	12	view →
KIRP	OS	Tertile	All	0.263	0.713	.024	9	view →
LUSC	DFS	Tertile	All	0.227	0.407	.048	3	view →
LIHC	DFS	Tertile	II,III,IV	0.757	0.190	.047	3	view →
THYM	DFS	Tertile	All	0.952	0.707	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

IGHVII-30-1–UCEC (OS)

Open the UCEC breakdown →