IGHVII-15-1

Across TCGA pan-cancer cohorts, IGHVII-15-1 RNA is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated IGHVII-15-1 data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher IGHVII-15-1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated IGHVII-15-1 expression acts as an unfavorable survival marker.

STAD, HNSC, and OV are the cancer types where IGHVII-15-1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	DFS	Tertile	All	0.148	0.548	<.001	126	view →
HNSC	OS	Tertile	III,IV	0.059	0.674	<.001	36	view →
OV	DFS	Tertile	All	0.310	0.542	.042	36	view →
SKCM	OS	Tertile	All	0.107	0.342	.007	24	view →
LUSC	OS	Tertile	II,III,IV	0.247	0.615	.041	18	view →
LUAD	DFS	Tertile	III,IV	0.206	0.670	.015	9	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

IGHVII-15-1–STAD (DFS)

Open the STAD breakdown →