IGHV6-1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGHV6-1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,866 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGHV6-1-associated proteins across cancer lineages are DOCK2, HCLS1, and IL16. Each is linked with IGHV6-1 in more than 9 cancer types. Because this analysis shows association rather than direction, both IGHV6-1-to-partner and partner-to-IGHV6-1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHV6-1→partner) and Y-score (partner→IGHV6-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCDOCK2 →+0.606+1.734<.001<.001310
BRCAHCLS1 →+0.509+2.007<.001<.001310
BRCAIL16 →+0.693+2.879<.001<.001310
OVWIPF1 →+0.597+2.573<.001<.001310
BRCAISG20 →+0.825+2.389<.001<.001310
OVMZB1 →+1.565+3.374<.001<.001310
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,866 associations by consensus.

Exploration