Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, IGHV5-51 mutation is significantly associated with the RNA expression of many other genes, with 277 significant associations in total. UCEC shows the largest number of these associations.
The most reproducible IGHV5-51-associated genes across cancer lineages are MIR325, RNU6-1213P, and MIR8059. Each is linked with IGHV5-51 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGHV5-51-to-partner and partner-to-IGHV5-51 results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (IGHV5-51→partner) and Y-score (partner→IGHV5-51) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.