Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, IGHV3-74 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. SKCM shows the largest number of these associations.
The most reproducible IGHV3-74-associated genes across cancer lineages are NF2, p38-MAPK_pT180_Y182, and Rad50. Each is linked with IGHV3-74 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGHV3-74-to-partner and partner-to-IGHV3-74 results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (IGHV3-74→partner) and Y-score (partner→IGHV3-74) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.