Across TCGA cell cohorts, IGHV3-72 protein abundance is significantly associated with the RNA expression of many other genes, with 2,705 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible IGHV3-72-associated genes across cancer lineages are RPS8, WDR46, and MRTO4. Each is linked with IGHV3-72 in more than 5 cancer types. Because this analysis shows association rather than direction, both IGHV3-72-to-partner and partner-to-IGHV3-72 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHV3-72→partner) and Y-score (partner→IGHV3-72) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	RPS8 →	+1.038	+0.942	<.001	.001	3	6
BONE	WDR46 →	+1.188	+0.592	.007	.005	3	6
LUNG_NSCLC_LUAD	MRTO4 →	+1.077	+0.626	<.001	<.001	3	6
LARGE_INTESTINE	RAD54L →	+0.576	+0.416	.003	.005	3	6
BREAST	RRP9 →	+0.654	+0.792	.008	.004	3	5
BREAST	FAAH2 →	-1.266	-0.814	.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,705 associations by consensus.

Exploration

IGHV3-72 survival (RNA) · tumor vs normal (RNA) · all IGHV3-72 data types