IGHV2-70D

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGHV2-70D RNA expression is significantly associated with the protein abundance of many other proteins, with 8,604 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGHV2-70D-associated proteins across cancer lineages are MZB1, CD38, and DOCK2. Each is linked with IGHV2-70D in more than 9 cancer types. Because this analysis shows association rather than direction, both IGHV2-70D-to-partner and partner-to-IGHV2-70D results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHV2-70D→partner) and Y-score (partner→IGHV2-70D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMZB1 →+1.296+2.292<.001<.001310
BRCACD38 →+1.145+2.302<.001<.00138
OVDOCK2 →+0.466+1.091<.001<.00138
LSCCTXNDC5 →+0.706+3.012<.001<.00137
GBMWAS →+0.393+0.168.003.00837
BRCARAC2 →+0.831+2.407<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,604 associations by consensus.

Exploration