Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, IGHV2-26 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. SKCM shows the largest number of these associations.
The most reproducible IGHV2-26-associated genes across cancer lineages are p53 and c-Jun_pS73. Each is linked with IGHV2-26 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGHV2-26-to-partner and partner-to-IGHV2-26 results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (IGHV2-26→partner) and Y-score (partner→IGHV2-26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.