IGHV1OR15-9

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGHV1OR15-9 mutation is significantly associated with the RNA expression of many other genes, with 265 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible IGHV1OR15-9-associated genes across cancer lineages are MIR4291, LINC02501, and SNORD8. Each is linked with IGHV1OR15-9 in more than 2 cancer types. Because this analysis shows association rather than direction, both IGHV1OR15-9-to-partner and partner-to-IGHV1OR15-9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHV1OR15-9→partner) and Y-score (partner→IGHV1OR15-9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LGGMIR4291 →+0.443+7.977<.001.00733
SKCMLINC02501 →+0.034+4.344<.001<.00132
LUADSNORD8 →+1.120+3.717<.001.00632
LUADTRDJ2 →+0.764+3.584<.001.00432
LUADRNU6-1267P →+0.502+3.514.005.00532
LUADHSPA8P17 →+0.027+4.197.007.00932
Each partner links to its Q-omics profile. Showing the 6 strongest of 265 associations by consensus.

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