IGHV1OR15-9

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGHV1OR15-9 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IGHV1OR15-9-associated genes across cancer lineages are Th2 cells, Hepatocytes, and CLP. Each is linked with IGHV1OR15-9 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGHV1OR15-9-to-partner and partner-to-IGHV1OR15-9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHV1OR15-9→partner) and Y-score (partner→IGHV1OR15-9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMTh2 cells →+0.217+3.706.006<.00132
UCECHepatocytes →+0.014+2.828.029.03632
SKCMCLP →+0.078+2.826.031.03531
UCECPericytes →+0.042+2.113.011.04431
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

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