IGHV1-69

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGHV1-69 protein abundance is significantly associated with the RNA expression of many other genes, with 403 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGHV1-69-associated genes across cancer lineages are COCH, PRELID3B, and SEC23B. Each is linked with IGHV1-69 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGHV1-69-to-partner and partner-to-IGHV1-69 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHV1-69→partner) and Y-score (partner→IGHV1-69) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCCOCH →-2.255-1.985.006.00921
LSCCPRELID3B →-1.483-1.985.002.00921
LSCCSEC23B →-0.654-1.985.005.00921
LSCCCRNKL1 →-1.183-1.985.004.00921
LSCCBEX4 →-1.356-1.985.001.00921
LSCCHCFC1R1 →-1.075-1.985.003.00921
Each partner links to its Q-omics profile. Showing the 6 strongest of 403 associations by consensus.

Exploration