Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, IGHV1-69 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.
The most reproducible IGHV1-69-associated genes across cancer lineages are TTTY2, USP9YP2, and CDY8P. Each is linked with IGHV1-69 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGHV1-69-to-partner and partner-to-IGHV1-69 results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (IGHV1-69→partner) and Y-score (partner→IGHV1-69) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.