IGHMBP2

Across TCGA patient cohorts, IGHMBP2 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,222 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IGHMBP2-associated proteins across cancer lineages are MCM3, MSH6, and ZC3H13_S265. Each is linked with IGHMBP2 in more than 4 cancer types. Because this analysis shows association rather than direction, both IGHMBP2-to-partner and partner-to-IGHMBP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGHMBP2 versus MCM3 in LSCC, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHMBP2→partner) and Y-score (partner→IGHMBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MCM3 →	+0.419	+0.599	.008	.002	3	4
HNSC	MSH6 →	+0.435	+0.721	.003	.006	2	5
PDAC	ZC3H13_S265 →	+0.671	+0.270	.001	<.001	3	4
LSCC	NUP153 →	+0.234	+0.579	<.001	<.001	3	4
LUAD	PDS5A_T1208 →	+0.544	+0.653	.001	.001	3	4
LSCC	SUPT6H →	+0.249	+0.757	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,222 associations by consensus.

IGHMBP2 vs MCM3 — LSCC

Explore this scatter interactively →