IGHMBP2

Across TCGA patient cohorts, IGHMBP2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,216 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible IGHMBP2-associated genes across cancer lineages are MRPL21, PPFIA1, and LTO1. Each is linked with IGHMBP2 in more than 3 cancer types. Because this analysis shows association rather than direction, both IGHMBP2-to-partner and partner-to-IGHMBP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGHMBP2 versus MRPL21 in HNSC, with a Pearson correlation of 0.68.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHMBP2→partner) and Y-score (partner→IGHMBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MRPL21 →	+0.815	+0.517	<.001	<.001	3	4
HNSC	PPFIA1 →	+0.933	+0.554	<.001	<.001	3	3
LSCC	LTO1 →	+1.176	+0.425	<.001	<.001	3	3
LSCC	TPCN2 →	+0.826	+0.437	<.001	<.001	3	3
LUAD	SVEP1 →	-0.757	-0.220	<.001	.001	3	3
CCRCC	MYEOV →	+1.412	+0.165	.002	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,216 associations by consensus.

IGHMBP2 vs MRPL21 — HNSC

Explore this scatter interactively →