IGHMBP2

Across TCGA cell cohorts, IGHMBP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,649 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible IGHMBP2-associated GO terms across cancer lineages are Signal transduction in response to DNA damage, Centriole replication, and Positive regulation of cell cycle checkpoint. Each is linked with IGHMBP2 in more than 14 cancer types. Because this analysis shows association rather than direction, both IGHMBP2-to-partner and partner-to-IGHMBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Signal transduction in response to DNA damage grouped by IGHMBP2-low versus IGHMBP2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHMBP2→partner) and Y-score (partner→IGHMBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Signal transduction in response to DNA damage →	+0.081	+0.717	.001	.001	3	15
BONE	Centriole replication →	+0.149	+1.221	<.001	<.001	3	14
OESOPHAGUS	Positive regulation of cell cycle checkpoint →	+0.117	+1.178	<.001	.002	3	14
BONE	Spindle localization →	+0.130	+0.960	.001	<.001	3	14
BONE	Centrosome cycle →	+0.084	+0.795	.001	.001	3	14
BLOOD_Lymphoma	Mitotic cell cycle checkpoint signaling →	+0.081	+0.658	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,649 associations by consensus.

Signal transduction in response to DNA damage by IGHMBP2 expression — BONE

Explore this box plot interactively →