IGHJ5

Across TCGA patient cohorts, IGHJ5 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,401 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGHJ5-associated proteins across cancer lineages are WAS, ZAP70, and DOCK2. Each is linked with IGHJ5 in more than 9 cancer types. Because this analysis shows association rather than direction, both IGHJ5-to-partner and partner-to-IGHJ5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGHJ5 versus WAS in GBM, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHJ5→partner) and Y-score (partner→IGHJ5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	WAS →	+0.662	+1.460	<.001	<.001	3	10
BRCA	ZAP70 →	+0.847	+3.049	<.001	<.001	3	10
GBM	DOCK2 →	+0.689	+1.565	<.001	<.001	3	10
GBM	HCLS1 →	+0.766	+1.497	<.001	<.001	3	10
BRCA	IL16 →	+0.669	+3.227	<.001	<.001	3	10
UCEC	RCSD1 →	+0.639	+2.592	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,401 associations by consensus.

IGHJ5 vs WAS — GBM

Explore this scatter interactively →