IGHJ4

Across TCGA patient cohorts, IGHJ4 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,840 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGHJ4-associated proteins across cancer lineages are MZB1, ARHGAP45, and CD48. Each is linked with IGHJ4 in more than 9 cancer types. Because this analysis shows association rather than direction, both IGHJ4-to-partner and partner-to-IGHJ4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGHJ4 versus MZB1 in OV, with a Pearson correlation of 0.59.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHJ4→partner) and Y-score (partner→IGHJ4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MZB1 →	+1.402	+3.475	<.001	<.001	3	10
LSCC	ARHGAP45 →	+0.503	+1.525	<.001	<.001	3	10
OV	CD48 →	+0.975	+3.846	<.001	<.001	3	10
LSCC	DOCK2 →	+0.627	+1.762	<.001	<.001	3	10
HNSC	DOCK8 →	+0.613	+2.875	<.001	<.001	3	10
GBM	HCLS1 →	+0.602	+1.086	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,840 associations by consensus.

IGHJ4 vs MZB1 — OV

Explore this scatter interactively →