IGHJ3

Across TCGA patient cohorts, IGHJ3 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,147 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGHJ3-associated proteins across cancer lineages are PTPRC, CD48, and DOCK2. Each is linked with IGHJ3 in more than 9 cancer types. Because this analysis shows association rather than direction, both IGHJ3-to-partner and partner-to-IGHJ3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGHJ3 versus PTPRC in BRCA, with a Pearson correlation of 0.63.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHJ3→partner) and Y-score (partner→IGHJ3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PTPRC →	+0.726	+2.775	<.001	<.001	3	10
OV	CD48 →	+1.039	+3.258	<.001	<.001	3	10
LSCC	DOCK2 →	+0.583	+1.799	<.001	<.001	3	10
BRCA	IL16 →	+0.636	+3.115	<.001	<.001	3	10
GBM	MZB1 →	+1.782	+0.834	<.001	<.001	3	10
OV	ARHGAP30 →	+0.604	+3.026	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,147 associations by consensus.

IGHJ3 vs PTPRC — BRCA

Explore this scatter interactively →