Across TCGA patient cohorts, IGHJ2 protein abundance is significantly associated with the RNA expression of many other genes, with 171 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible IGHJ2-associated genes across cancer lineages are GZMB, LAMA1, and MEFV. Each is linked with IGHJ2 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGHJ2-to-partner and partner-to-IGHJ2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHJ2→partner) and Y-score (partner→IGHJ2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	GZMB →	-1.829	-1.810	.003	.009	3	1
LUAD	LAMA1 →	-0.789	-1.542	.004	.007	3	1
LUAD	MEFV →	-0.832	-1.985	<.001	.002	3	1
LUAD	NFKB1 →	-0.615	-1.443	<.001	.003	3	1
LUAD	RAB35 →	-0.552	-1.727	.009	.005	3	1
LUAD	TENT5A →	-1.420	-2.025	.004	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 171 associations by consensus.

Exploration

IGHJ2 survival (RNA) · tumor vs normal (RNA) · all IGHJ2 data types