Across TCGA patient cohorts, IGHJ2 protein abundance is significantly associated with the protein abundance of many other proteins, with 201 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible IGHJ2-associated proteins across cancer lineages are NBEA, CEP170, and CTNNA1_S851. Each is linked with IGHJ2 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGHJ2-to-partner and partner-to-IGHJ2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHJ2→partner) and Y-score (partner→IGHJ2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	NBEA →	+0.814	+1.767	.001	.004	3	1
LUAD	CEP170 →	-0.475	-1.985	<.001	.002	3	1
LUAD	CTNNA1_S851 →	+0.693	+1.910	<.001	.007	3	1
LUAD	IDH1 →	+0.657	+1.859	<.001	.001	2	1
LUAD	S100A8 →	-2.273	-2.016	<.001	.008	2	1
LUAD	S100A9_T113 →	-1.772	-1.987	<.001	.002	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 201 associations by consensus.

Exploration

IGHJ2 survival (RNA) · tumor vs normal (RNA) · all IGHJ2 data types