Across TCGA pan-cancer cohorts, IGHJ1P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of IGHJ1P’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where IGHJ1P RNA is repressed in tumor relative to normal tissue. In most cancer types IGHJ1P is over-expressed in tumor, although a few such as COAD show the opposite, repressed pattern.

COAD, LUAD, and BRCA are the cancer types where IGHJ1P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in IGHJ1P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	−0.603	<.001	4	view →
LUAD	All	All	+0.367	.002	2	view →
BRCA	Female	II,III,IV	+0.133	.025	2	view →
KIRC	All	All	+0.109	.034	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: IGHJ1P RNA expression & survival · all IGHJ1P data types