Across TCGA patient cohorts, IGHJ1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,387 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGHJ1-associated proteins across cancer lineages are MZB1, IRF4, and CD38. Each is linked with IGHJ1 in more than 8 cancer types. Because this analysis shows association rather than direction, both IGHJ1-to-partner and partner-to-IGHJ1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHJ1→partner) and Y-score (partner→IGHJ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MZB1 →	+1.102	+1.495	<.001	.003	3	9
LSCC	IRF4 →	+1.044	+2.060	<.001	<.001	3	9
LSCC	CD38 →	+0.987	+1.941	<.001	<.001	3	9
LSCC	SEPTIN1 →	+0.757	+1.449	<.001	<.001	3	8
LSCC	IL16 →	+0.580	+1.742	<.001	<.001	3	8
BRCA	CD48 →	+0.725	+1.792	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,387 associations by consensus.

Exploration

IGHJ1 survival (RNA) · tumor vs normal (RNA) · all IGHJ1 data types