Across TCGA patient cohorts, IGHG3 RNA expression is significantly associated with the mutation status of many other genes, with 11,481 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IGHG3-associated genes across cancer lineages are TTN, BRAF, and TP53. Each is linked with IGHG3 in more than 3 cancer types. Because this analysis shows association rather than direction, both IGHG3-to-partner and partner-to-IGHG3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHG3→partner) and Y-score (partner→IGHG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	TTN →	-1.247	-1.045	<.001	.001	3	4
UCEC	BRAF →	+3.807	+2.007	<.001	.001	3	3
HNSC	TP53 →	-0.604	-0.825	.001	<.001	3	3
HNSC	TRPC5 →	+3.494	+2.432	.002	.002	2	4
COAD	NBEA →	+2.999	+1.472	<.001	.001	3	3
COAD	LRRC7 →	+4.321	+1.763	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,481 associations by consensus.

Exploration

IGHG3 survival (RNA) · tumor vs normal (RNA) · all IGHG3 data types