Across TCGA patient cohorts, IGHG3 protein abundance is significantly associated with the protein abundance of many other proteins, with 14,372 significant associations in total. COAD shows the largest number of these associations.

The most reproducible IGHG3-associated proteins across cancer lineages are IGHG1, IGHG2, and IGHV3-15. Each is linked with IGHG3 in more than 9 cancer types. Because this analysis shows association rather than direction, both IGHG3-to-partner and partner-to-IGHG3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHG3→partner) and Y-score (partner→IGHG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	IGHG1 →	+0.852	+0.748	<.001	<.001	3	10
CCRCC	IGHG2 →	+0.865	+1.004	<.001	<.001	3	10
OV	IGHV3-15 →	+0.802	+0.668	<.001	<.001	3	10
OV	IGHV3-35 →	+0.867	+1.064	<.001	<.001	3	10
OV	IGHV3-49 →	+1.200	+1.184	<.001	<.001	3	10
OV	IGHV3-7 →	+1.005	+0.786	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,372 associations by consensus.

Exploration

IGHG3 survival (RNA) · tumor vs normal (RNA) · all IGHG3 data types