Across TCGA patient cohorts, IGHG3 mutation is significantly associated with the RNA expression of many other genes, with 629 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IGHG3-associated genes across cancer lineages are RNU6ATAC3P, ABCD1P5, and MIR4290HG. Each is linked with IGHG3 in more than 2 cancer types. Because this analysis shows association rather than direction, both IGHG3-to-partner and partner-to-IGHG3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHG3→partner) and Y-score (partner→IGHG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6ATAC3P →	+0.511	+4.178	<.001	.009	3	3
LUAD	ABCD1P5 →	+0.061	+3.074	<.001	.005	3	3
CESC	MIR4290HG →	+0.020	+4.551	.002	.004	3	3
STAD	MIR6775 →	+0.719	+3.381	.003	.008	3	3
SKCM	MIR3145 →	+0.260	+1.320	.004	.001	3	3
DLBC	MIR6865 →	+0.623	+4.357	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 629 associations by consensus.

Exploration

IGHG3 survival (RNA) · tumor vs normal (RNA) · all IGHG3 data types