Across TCGA patient cohorts, IGHG2 protein abundance is significantly associated with the RNA expression of many other genes, with 13,998 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IGHG2-associated genes across cancer lineages are CCDC80, CXCL12, and CDO1. Each is linked with IGHG2 in more than 5 cancer types. Because this analysis shows association rather than direction, both IGHG2-to-partner and partner-to-IGHG2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHG2→partner) and Y-score (partner→IGHG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CCDC80 →	+1.479	+0.686	<.001	<.001	3	6
COAD	CXCL12 →	+1.418	+0.732	<.001	<.001	3	5
OV	CDO1 →	+1.020	+0.740	.001	<.001	3	5
GBM	COLEC12 →	+1.103	+0.711	<.001	<.001	3	5
OV	MIR100HG →	+0.935	+0.752	.003	<.001	3	5
HNSC	UCHL5 →	-0.571	-0.403	.002	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,998 associations by consensus.

Exploration

IGHG2 survival (RNA) · tumor vs normal (RNA) · all IGHG2 data types