IGHD5OR15-5B

Across TCGA patient cohorts, IGHD5OR15-5B RNA expression is significantly associated with the go_rna of many other GO terms, with 2,271 significant associations in total. STAD shows the largest number of these associations.

The most reproducible IGHD5OR15-5B-associated GO terms across cancer lineages are Negative regulation of extrinsic apoptotic signaling pathway, Positive regulation of striated muscle cell differentiation, and Obsolete selective autophagy. Each is linked with IGHD5OR15-5B in more than 2 cancer types. Because this analysis shows association rather than direction, both IGHD5OR15-5B-to-partner and partner-to-IGHD5OR15-5B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of extrinsic apoptotic signaling pathway grouped by IGHD5OR15-5B-low versus IGHD5OR15-5B-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHD5OR15-5B→partner) and Y-score (partner→IGHD5OR15-5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of extrinsic apoptotic signaling pathway →	+0.188	+0.102	<.001	.005	3	2
STAD	Positive regulation of striated muscle cell differentiation →	+0.076	+0.100	<.001	.006	3	2
STAD	Obsolete selective autophagy →	+0.230	+0.146	<.001	.006	3	2
STAD	Negative regulation of gluconeogenesis →	+0.181	+0.206	<.001	.004	3	2
STAD	Carbohydrate biosynthetic process →	+0.169	+0.174	<.001	.002	3	2
STAD	Carbohydrate catabolic process →	+0.199	+0.215	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,271 associations by consensus.

Negative regulation of extrinsic apoptotic signaling pathway by IGHD5OR15-5B expression — STAD

Explore this box plot interactively →