IGHD5OR15-5A

Across TCGA patient cohorts, IGHD5OR15-5A RNA expression is significantly associated with the go_rna of many other GO terms, with 757 significant associations in total. STAD shows the largest number of these associations.

The most reproducible IGHD5OR15-5A-associated GO terms across cancer lineages are Negative regulation of tubulin deacetylation, Iron-sulfur cluster assembly, and Alpha-amino acid metabolic process. Each is linked with IGHD5OR15-5A in more than 1 cancer types. Because this analysis shows association rather than direction, both IGHD5OR15-5A-to-partner and partner-to-IGHD5OR15-5A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of tubulin deacetylation grouped by IGHD5OR15-5A-low versus IGHD5OR15-5A-high in LGG.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHD5OR15-5A→partner) and Y-score (partner→IGHD5OR15-5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	Negative regulation of tubulin deacetylation →	+0.055	+0.063	.001	.003	3	1
STAD	Iron-sulfur cluster assembly →	+0.266	+0.160	<.001	.006	3	1
STAD	Alpha-amino acid metabolic process →	+0.180	+0.168	<.001	.002	3	1
STAD	Regulation of peptidyl-serine phosphorylation →	+0.179	+0.141	<.001	.007	3	1
STAD	Response to tumor necrosis factor →	+0.247	+0.160	<.001	.005	3	1
STAD	Tetrahydrofolate metabolic process →	+0.231	+0.074	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 757 associations by consensus.

Negative regulation of tubulin deacetylation by IGHD5OR15-5A expression — LGG

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