Across TCGA patient cohorts, IGHD5-18 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,879 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IGHD5-18-associated GO terms across cancer lineages are B cell receptor signaling pathway, Negative regulation of lymphocyte apoptotic process, and B cell mediated immunity. Each is linked with IGHD5-18 in more than 13 cancer types. Because this analysis shows association rather than direction, both IGHD5-18-to-partner and partner-to-IGHD5-18 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHD5-18→partner) and Y-score (partner→IGHD5-18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	B cell receptor signaling pathway →	+0.130	+0.226	<.001	<.001	3	14
COAD	Negative regulation of lymphocyte apoptotic process →	+0.119	+0.076	<.001	.007	2	13
THCA	B cell mediated immunity →	+0.126	+0.131	<.001	<.001	3	12
SKCM	Regulation of lymphocyte apoptotic process →	+0.086	+0.241	<.001	<.001	3	11
COAD	T cell apoptotic process →	+0.102	+0.129	<.001	.004	2	12
COAD	Negative regulation of T cell apoptotic process →	+0.116	+0.141	<.001	.009	1	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,879 associations by consensus.

Exploration

IGHD5-18 survival (RNA) · tumor vs normal (RNA) · all IGHD5-18 data types