IGHD4OR15-4A

Across TCGA patient cohorts, IGHD4OR15-4A RNA expression is significantly associated with the protein abundance of many other proteins, with 20 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IGHD4OR15-4A-associated proteins across cancer lineages are MYEF2_S498, NEK7, and NUDT5. Each is linked with IGHD4OR15-4A in more than 1 cancer types. Because this analysis shows association rather than direction, both IGHD4OR15-4A-to-partner and partner-to-IGHD4OR15-4A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGHD4OR15-4A versus MYEF2_S498 in GBM, with a Pearson correlation of 0.26.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHD4OR15-4A→partner) and Y-score (partner→IGHD4OR15-4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MYEF2_S498 →	+0.639	+0.381	.008	.009	3	1
GBM	NEK7 →	+0.456	+0.381	<.001	.009	3	1
GBM	NUDT5 →	+0.474	+0.543	.001	.009	3	1
GBM	P2RY1_S354 →	-1.342	-0.779	<.001	.009	3	1
GBM	REPS2_S544 →	+0.773	+0.459	.002	.009	3	1
GBM	IMPDH2_S160 →	+0.851	+0.814	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

IGHD4OR15-4A vs MYEF2_S498 — GBM

Explore this scatter interactively →