IGFN1

Across TCGA patient cohorts, IGFN1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,361 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IGFN1-associated proteins across cancer lineages are GTPBP4, AGO1, and FANCD2. Each is linked with IGFN1 in more than 4 cancer types. Because this analysis shows association rather than direction, both IGFN1-to-partner and partner-to-IGFN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGFN1 versus GTPBP4 in BRCA, with a Pearson correlation of -0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGFN1→partner) and Y-score (partner→IGFN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GTPBP4 →	-0.505	-0.467	<.001	<.001	3	5
UCEC	AGO1 →	+0.270	+1.256	<.001	<.001	3	4
COAD	FANCD2 →	-1.070	-1.295	<.001	.009	3	4
BRCA	GNG12 →	+0.411	+0.399	<.001	<.001	3	4
UCEC	GNPDA2 →	+0.423	+1.136	<.001	.001	3	4
UCEC	HDGFL3 →	+0.771	+1.269	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,361 associations by consensus.

IGFN1 vs GTPBP4 — BRCA

Explore this scatter interactively →