IGFN1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGFN1 protein abundance is significantly associated with the protein abundance of many other proteins, with 2,814 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible IGFN1-associated proteins across cancer lineages are CEP290, DES_S438, and RHBDF2_S387. Each is linked with IGFN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGFN1-to-partner and partner-to-IGFN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGFN1 versus CEP290 in OV, with a Pearson correlation of 0.57.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGFN1→partner) and Y-score (partner→IGFN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVCEP290 →+1.077+1.390<.001<.00132
HNSCDES_S438 →+1.181+0.897.001<.00132
OVRHBDF2_S387 →-1.417-2.314<.001<.00132
HNSCRPL3L →+1.167+0.852<.001<.00132
HNSCTCAP →+1.175+0.774<.001.00132
HNSCUNC45B →+0.962+0.817<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,814 associations by consensus.

IGFN1 vs CEP290 — OV

Per-sample scatter of IGFN1 vs CEP290 in OV (Pearson r = 0.57).

Explore this scatter interactively →

Exploration