IGFLR1

Across TCGA patient cohorts, IGFLR1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,529 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGFLR1-associated genes across cancer lineages are CYTH4, NCF4, and CSF2RB. Each is linked with IGFLR1 in more than 4 cancer types. Because this analysis shows association rather than direction, both IGFLR1-to-partner and partner-to-IGFLR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGFLR1 versus CYTH4 in HNSC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGFLR1→partner) and Y-score (partner→IGFLR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CYTH4 →	+1.155	+1.056	<.001	<.001	3	5
BRCA	NCF4 →	+0.985	+0.915	<.001	<.001	3	5
HNSC	CSF2RB →	+1.033	+0.982	<.001	<.001	3	5
PDAC	GZMB →	+1.642	+0.722	.001	.008	3	5
HNSC	IL21R →	+0.846	+0.791	<.001	<.001	3	5
BRCA	IL4I1 →	+0.836	+0.612	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,529 associations by consensus.

IGFLR1 vs CYTH4 — HNSC

Explore this scatter interactively →