Across TCGA patient cohorts, IGFL4 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IGFL4-associated genes across cancer lineages are CD4+ Tcm, CD8+ Tem, and Melanocytes. Each is linked with IGFL4 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGFL4-to-partner and partner-to-IGFL4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGFL4→partner) and Y-score (partner→IGFL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CD4+ Tcm →	+0.007	+5.468	<.001	.043	3	1
UCEC	CD8+ Tem →	+0.004	+5.066	<.001	.033	3	1
UCEC	Melanocytes →	-0.012	-2.946	.046	.037	2	1
UCEC	Macrophages M1 →	+0.030	+3.010	<.001	.020	1	1
UCEC	MEP →	+0.047	+3.010	.003	.020	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

IGFL4 survival (RNA) · tumor vs normal (RNA) · all IGFL4 data types