Across TCGA patient cohorts, IGFL2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,153 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible IGFL2-associated proteins across cancer lineages are VCAN, RCN3, and HTRA3. Each is linked with IGFL2 in more than 7 cancer types. Because this analysis shows association rather than direction, both IGFL2-to-partner and partner-to-IGFL2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGFL2→partner) and Y-score (partner→IGFL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	VCAN →	+1.399	+1.995	<.001	<.001	3	8
OV	RCN3 →	+0.730	+2.017	<.001	<.001	3	8
OV	HTRA3 →	+0.940	+2.205	<.001	<.001	3	8
BRCA	NXN →	+0.666	+0.928	<.001	<.001	3	8
OV	SULF1 →	+1.023	+2.385	<.001	<.001	3	8
CCRCC	THBS2 →	+1.517	+0.928	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,153 associations by consensus.

Exploration

IGFL2 survival (RNA) · tumor vs normal (RNA) · all IGFL2 data types