IGFL2-AS1

Across TCGA pan-cancer cohorts, IGFL2-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated IGFL2-AS1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher IGFL2-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated IGFL2-AS1 expression acts as an unfavorable survival marker, although some lineages such as ACC and CESC show a favorable association.

MESO, KIRC, and ACC are the cancer types where IGFL2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Median	II,III,IV	0.272	0.529	<.001	123	view →
KIRC	DFS	Median	All	0.560	0.687	<.001	102	view →
ACC	DFS	Quartile	III,IV	0.796	0.251	<.001	59	view →
CESC	OS	Median	II,III,IV	0.920	0.719	<.001	58	view →
HNSC	OS	Tertile	All	0.710	0.806	.003	44	view →
LGG	OS	Median	All	0.860	0.756	<.001	34	view →
COAD	DFS	Quartile	All	0.577	0.747	.004	24	view →
OV	DFS	Median	III,IV	0.492	0.569	.011	18	view →
ESCA	DFS	Tertile	IV	0.704	0.226	.024	15	view →
STAD	DFS	Quartile	IV	0.146	0.620	.024	12	view →
READ	DFS	Tertile	IV	0.396	0.756	.003	12	view →
SKCM	DFS	Tertile	II,III,IV	0.370	0.168	.014	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

IGFL2-AS1–MESO (DFS)

Open the MESO breakdown →