IGFBPL1

Across TCGA patient cohorts, IGFBPL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,777 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGFBPL1-associated proteins across cancer lineages are SSH3, KDM3A, and ZNF687. Each is linked with IGFBPL1 in more than 4 cancer types. Because this analysis shows association rather than direction, both IGFBPL1-to-partner and partner-to-IGFBPL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGFBPL1 versus SSH3 in GBM, with a Pearson correlation of -0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGFBPL1→partner) and Y-score (partner→IGFBPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SSH3 →	-0.364	-1.497	.003	.002	3	5
LSCC	KDM3A →	+0.327	+0.801	<.001	<.001	3	5
COAD	ZNF687 →	+0.354	+0.971	.005	.001	3	4
HNSC	RAB6B →	+1.223	+1.416	<.001	<.001	3	4
LSCC	PTBP2 →	+1.217	+1.478	<.001	<.001	3	4
HNSC	CENPF →	+0.668	+1.031	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,777 associations by consensus.

IGFBPL1 vs SSH3 — GBM

Explore this scatter interactively →