IGFBPL1

Across TCGA cell cohorts, IGFBPL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,694 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible IGFBPL1-associated GO terms across cancer lineages are Protein-DNA complex assembly, Cell cycle phase transition, and DNA-templated transcription initiation. Each is linked with IGFBPL1 in more than 11 cancer types. Because this analysis shows association rather than direction, both IGFBPL1-to-partner and partner-to-IGFBPL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein-DNA complex assembly grouped by IGFBPL1-low versus IGFBPL1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGFBPL1→partner) and Y-score (partner→IGFBPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Protein-DNA complex assembly →	+0.070	+2.779	<.001	<.001	3	12
SOFT_TISSUE	Cell cycle phase transition →	+0.094	+2.734	<.001	<.001	3	11
BONE	DNA-templated transcription initiation →	+0.086	+2.408	.005	.001	3	11
UPPER_AERODIGESTIVE_TRACT	Transcription initiation at RNA polymerase II promoter →	+0.080	+0.751	<.001	.004	3	10
SKIN	U2-type prespliceosome assembly →	+0.059	+0.685	.003	.002	3	10
SKIN	ATP synthesis coupled electron transport →	+0.084	+0.748	<.001	.006	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,694 associations by consensus.

Protein-DNA complex assembly by IGFBPL1 expression — SOFT_TISSUE

Explore this box plot interactively →