IGFBP7

Across TCGA patient cohorts, IGFBP7 RNA expression is significantly associated with the protein abundance of many other proteins, with 26,137 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IGFBP7-associated proteins across cancer lineages are SVIL_S547, PRKG1, and RSU1. Each is linked with IGFBP7 in more than 9 cancer types. Because this analysis shows association rather than direction, both IGFBP7-to-partner and partner-to-IGFBP7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGFBP7 versus SVIL_S547 in OV, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGFBP7→partner) and Y-score (partner→IGFBP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SVIL_S547 →	+1.093	+0.939	.001	.002	3	10
CCRCC	PRKG1 →	+0.700	+0.955	<.001	<.001	3	10
OV	RSU1 →	+0.468	+1.362	<.001	<.001	3	10
BRCA	CLEC3B →	+0.757	+0.826	<.001	<.001	3	10
BRCA	SSC5D →	+0.924	+0.796	<.001	<.001	3	9
CCRCC	TAGLN →	+1.160	+0.846	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 26,137 associations by consensus.

IGFBP7 vs SVIL_S547 — OV

Explore this scatter interactively →